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Antigenic Specificity | KRT17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial stem cells. Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17 |
Immunogen | Immunogen: Recombinant Bovine Keratin, type I cytoskeletal 17 protein |
Other Names | [Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17; KRT17] |
Gene, Accession # | [KRT17], Gene ID: 281889, NCBI: NP_001098792.1, UniProt: A1L595 |
Catalog # | MBS7000813 |
Price | $160, $235 |
Order / More Info | KRT17 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |