Human STAM-binding protein Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Human STAM-binding protein |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization.Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways. |
| Immunogen | Immunogen: Recombinant human STAM-binding protein protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109051 / sc-109053 / sc-98765 |
| Other Names | [Associated molecule with the SH3 domain of STAM; Endosome-associated ubiquitin isopeptidase; STAMBP; AMSH], [STAMBP; STAMBP; AMSH; MICCAP; AMSH] |
| Gene, Accession # | [STAM], Gene ID: 10617, NCBI: NP_006454.1, UniProt: O95630 |
| Catalog # | MBS1488605 |
| Price | $160, $235 |
| Order / More Info | Human STAM-binding protein Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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