POLR3F Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPOLR3F
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatfluorescein (FITC) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
ImmunogenImmunogen: Recombinant human DNA-directed RNA polymerase III subunit RPC6 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32125 / sc-32126
Other Names[DNA-directed RNA polymerase III subunit RPC6; RNA polymerase III subunit C6; POLR3F; DNA-directed RNA polymerase III subunit F; RNA polymerase III 39 kDa subunit; RPC39], [POLR3F; POLR3F; RPC6; RPC39; RNA polymerase III subunit C6; RPC39]
Gene, Accession #[POLR3F], Gene ID: 10621, NCBI: NP_001269455.1, UniProt: Q9H1D9
Catalog #MBS969117
Price$160, $235
Order / More InfoPOLR3F Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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