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Antigenic Specificity | NCK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NCK2 protein. Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.Susanne Frese, J. Biol. Chem., Jun 2006; 281: 18236 - 18245. Friedhelm Bladt, Mol. Cell. Biol., Jul 2003; 23: 4586 - 4597. Stephan J. Kempiak, J. Biol. Chem., Feb 2005; 280: 5836 - 5842.Min Chen, Mol. Cell. Biol., Nov 2000; 20: 7867 - 7880. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human NCK2. |
Other Names | [Cytoplasmic protein NCK2; GRB4; NCK adaptor protein 2; NCKbeta; Nck-2] |
Gene, Accession # | [NCK2], Gene ID: 8440, NCBI: NP_001004720.1, UniProt: O43639 |
Catalog # | MBS9412609 |
Price | $200, $255 |
Order / More Info | NCK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |