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Antigenic Specificity | uPAR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: uPAR antibody detects endogenous levels of uPAR. Function: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.Subunit Structure: Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Interacts with SORL1. Interacts with FAP (seprase); the interaction occurs at the cell surface of invadopodia membrane. |
Immunogen | Immunogen: A synthesized peptide derived from human uPAR. Subcellular Location: Secreted and Cell Membrane. Tissue Specificity: Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
Other Names | [CD 87; CD87; CD87 antigen; MO 3; MO3; Monocyte activation antigen Mo3; Plasminogen activator receptor urokinase; Plasminogen activator urokinase receptor; PLAUR; U PAR; u plasminogen activator receptor; U-PAR; u-plasminogen activator receptor form 2; UPA receptor; uPAR; UPAR_HUMAN; Urinary plasminogen activator receptor; URKR; Urokinase plasminogen activator receptor; Urokinase plasminogen activator surface receptor; urokinase-type plasminogen activator (uPA) receptor] |
Gene, Accession # | [PLAUR], Gene ID: 5329, NCBI: NP_001005376.1, UniProt: Q03405 |
Catalog # | MBS9603723 |
Price | $240, $280 |
Order / More Info | uPAR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |