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Antigenic Specificity | Daxx |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Death domain-associated protein 6(DAXX) detection. Tested with WB in Human, Mouse, Rat. Background: DAXX(death-domain associated protein) also known as DAP6(Death-associated protein 6) or BING2, was first discovered through its cytoplasmic interaction with the classical death receptor Fas. Human DAXX encodes a 740-amino acid polypeptide containing a nuclear localization signal. Functional analyses by Yang et al.(1997) demonstrated that Daxx binds to the Fas death domain and enhances Fas-mediated apoptosis. The authors suggested that DAXX and FADD define 2 distinct apoptotic pathways downstream of Fas. The DAXX gene is mapped to human chromosome 6p21.3 by somatic cell hybrid panels and fluoresc |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Daxx (325-341aa QERRHLDLIYNFGCHLT), identical to the related mouse and rat sequences. |
Other Names | [Death domain-associated protein 6; death-domain associated protein;; BING 2; BING2; CENP-C binding protein; DAP 6; DAP6; Daxx; DAXX; DAXX_HUMAN; Death associated protein 6; Death domain associated protein 6; Death domain associated protein; Death domain-associated protein 6; EAP 1; EAP1; ETS1 associated protein 1; ETS1-associated protein 1; Fas binding protein; Fas death domain associated protein; Fas death domain-associated protein; hDaxx; MGC126245; MGC126246], [DAXX; DAXX; DAP6; EAP1; BING2; BING2; DAP6; hDaxx; EAP1] |
Gene, Accession # | [DAXX], Gene ID: 1616, NCBI: Q9UER7.2, UniProt: Q9UER7 |
Catalog # | MBS176018 |
Price | $280 |
Order / More Info | Daxx Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |