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Antigenic Specificity | BAP1 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: BAP1, also known as BRCA1-associated protein-1, contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 is a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. BAP1 is expressed as a 4-kb mRNA in all human tissues, and mapped to 3p21.3.Protein Function: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell gr |
Immunogen | Immunogen: E Coli-derived human BAP1 recombinant protein (Position: M1-E278). Subcellular Localization: Cytoplasm. Tissue Specificity: Highly expressed in testis, placenta and ovary. Expressed in breast. |
Other Names | [Ubiquitin carboxyl-terminal hydrolase BAP1; BRCA1-associated protein 1; Cerebral protein 6; BAP1; KIAA0272; hucep-6] |
Gene, Accession # | [BAP1], Gene ID: 8314, NCBI: NP_004647.1, UniProt: Q92560 |
Catalog # | MBS1750375 |
Price | $280 |
Order / More Info | BAP1 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |