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Antigenic Specificity | PIG SURFACTANT PROTEIN D |
Clone | [1.7] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.25 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Immunofluorescence (IF), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects porcine surfactant protein D (pSP-D), a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs. M |
Immunogen | Immunogen: Purified porcine surfactant protein D Histology Positive Control Tissue: Porcine lung tissue Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of theP3X63Ag.8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Pig |
Other Names | [pulmonary surfactant-associated protein D; Pulmonary surfactant-associated protein D; pulmonary surfactant-associated protein D; lung surfactant protein D; surfactant, pulmonary-associated protein D; Lung surfactant protein D], [SFTPD; SFTPD; SP-D; PSP-D; PSP-D; SP-D] |
Gene, Accession # | Gene ID: 397198, NCBI: NP_999275.1, UniProt: Q9N1X4 |
Catalog # | MBS219620 |
Price | $450 |
Order / More Info | PIG SURFACTANT PROTEIN D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |