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Antigenic Specificity | TSG101 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 0.5-1.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).< |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 330-390 on Tumor susceptibility gene 101 protein. Conjugation: Unconjugated |
Other Names | [Affinity Purified Tumor susceptibility gene 101 protein; ESCRT I complex subunit TSG101; TS101_HUMAN; TSG 10; TSG 101; Tumor susceptibility gene 10; Tumor susceptibility gene 101; Tumor susceptibility protein; Tumor susceptibility protein isoform 3; VPS23] |
Gene, Accession # | [TSG101], Gene ID: 7251, NCBI: NP_006283.1, UniProt: Q99816 |
Catalog # | MBS5400834 |
Price | $390 |
Order / More Info | TSG101 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |