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Antigenic Specificity | Human CASPASE-5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human Caspase-5 antibody recognizes an epitope located within the internal region of human Caspase-5, a 47kDa cysteine protease, otherwise known as ICH-3. Caspase-5 has been shown to be expressed at higher levels in the colon, lung, spleen, small intestine and by peripheral blood lymphocytes. Caspase-5 is a member of a growing number of inflammatory caspases belonging to the Caspase-1 (ICE-type) subfamily, which require proteolytic processing of their inactive precursor into smaller active subunits. Unlike Caspase-1, Caspase-5 is not directly responsible for the activation of IL-1Beta from the pro-IL-1Beta precursor, but the presence of Caspase-5 does appear to enhance the processing of IL-1Beta. The in vivo expression of Caspas |
Immunogen | Perservative Stabilisers: 0.02% Sodium Azide. Preparation: Antisera to human Caspase-5 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. |
Other Names | [caspase-5 isoform b; Caspase-5; caspase-5; CASP-5; ICE(rel)-III; TY protease; caspase 5, apoptosis-related cysteine protease; protease ICH-3; protease TY; caspase 5, apoptosis-related cysteine peptidase; ICE(rel)-III; Protease ICH-3; Protease TYCleaved into the following 2 chains:Caspase-5 subunit p20; Caspase-5 subunit p10], [CASP5; CASP5; ICH-3; ICEREL-III; ICE(rel)III; ICH3; CASP-5] |
Gene, Accession # | Gene ID: 838, NCBI: NP_001129581.1, UniProt: P51878 |
Catalog # | MBS221846 |
Price | $375 |
Order / More Info | Human CASPASE-5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |