Human CASPASE-5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CASPASE-5
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionRabbit anti Human Caspase-5 antibody recognizes an epitope located within the internal region of human Caspase-5, a 47kDa cysteine protease, otherwise known as ICH-3. Caspase-5 has been shown to be expressed at higher levels in the colon, lung, spleen, small intestine and by peripheral blood lymphocytes. Caspase-5 is a member of a growing number of inflammatory caspases belonging to the Caspase-1 (ICE-type) subfamily, which require proteolytic processing of their inactive precursor into smaller active subunits. Unlike Caspase-1, Caspase-5 is not directly responsible for the activation of IL-1Beta from the pro-IL-1Beta precursor, but the presence of Caspase-5 does appear to enhance the processing of IL-1Beta. The in vivo expression of Caspas
ImmunogenPerservative Stabilisers: 0.02% Sodium Azide. Preparation: Antisera to human Caspase-5 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Other Names[caspase-5 isoform b; Caspase-5; caspase-5; CASP-5; ICE(rel)-III; TY protease; caspase 5, apoptosis-related cysteine protease; protease ICH-3; protease TY; caspase 5, apoptosis-related cysteine peptidase; ICE(rel)-III; Protease ICH-3; Protease TYCleaved into the following 2 chains:Caspase-5 subunit p20; Caspase-5 subunit p10], [CASP5; CASP5; ICH-3; ICEREL-III; ICE(rel)III; ICH3; CASP-5]
Gene, Accession #Gene ID: 838, NCBI: NP_001129581.1, UniProt: P51878
Catalog #MBS221846
Price$375
Order / More InfoHuman CASPASE-5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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