A1Up Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | A1Up |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: A1Up antibody detects endogenous levels of total A1Up. Function: Plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome (PubMed:15280365). Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). Acts as an adapter protein that recruits UBQLN1 to the autophagy machinery. Mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of au |
| Immunogen | Immunogen: A synthesized peptide derived from human A1Up Subcellular Location: Nucleus. Cytoplasm. Endoplasmic Reticulum. May associate with the endoplasmic reticulum. Tissue Specificity: Highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (10 |
| Other Names | [28S ribosomal protein S7; A1U; A1Up; AI663987; Ataxin 1 interacting ubiquitin like protein; Ataxin 1 ubiquitin like interacting protein A1U; Ataxin 1 ubiquitin like interacting protein; Ataxin-1 ubiquitin-like-interacting protein A1U; bMRP 27a; bMRP27a; C1orf6; CIP75; Connexin43 interacting protein of 75 kDa; MRP S7; RGD1308273; S7mt; UBIN; Ubiquilin 4; Ubiquilin-4; UBQL4_HUMAN; UBQLN4] |
| Gene, Accession # | [A1Up], Gene ID: 56893, NCBI: NP_001291271.1, UniProt: Q9NRR5 |
| Catalog # | MBS9602045 |
| Price | $240, $280 |
| Order / More Info | A1Up Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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