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Antigenic Specificity | BMP2 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Induces cartilage and bone formation (PubMed: 3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed: 24362451). |
Immunogen | Immunogen: A synthesized peptide derived from human BMP2. Subcellular Localization: Secreted. Tissue Specificity: Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. |
Other Names | [Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A; BMP2; BMP2A], [BMP2; BMP2; BDA2; BMP2A; BMP2A; BMP-2; BMP-2A] |
Gene, Accession # | [BMP2], Gene ID: 650, NCBI: NP_001191.1, UniProt: P12643 |
Catalog # | MBS179275 |
Price | $160, $340, $340 |
Order / More Info | BMP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |