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Antigenic Specificity | CST3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CST3 antibody. Cystatin C is a 14 kDa member of the Cystatin superfamily of cysteine protease inhibitors (1). Most cell types secrete Cystatin C (1). Cystatin C inhibits cathepsins, and thereby may function as a tumor suppressor by inhibiting cathepsin mediated tumor cell invasion (2). In addition, this tumor suppressor function can also be attributed to Cystatin C's ability to antagonize TGF-b1 signaling (2,3). Cystatin C may also modulate antigen presentation through its ability to inhibit cathepsins (4). Cystatin C is also a biomarker for kidney dysfunction (5). |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CST3. |
Other Names | [ARMD11; MGC117328; CST3] |
Gene, Accession # | [CST3], Gene ID: 1471, NCBI: NP_000090.1, UniProt: P01034 |
Catalog # | MBS9403993 |
Price | $255 |
Order / More Info | CST3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |