TAB2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTAB2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionSpecificity: TAB2 antibody is human specific. TAB2 antibody is predicted not to cross-react with other TAB proteins. TAB2 Antibody: TAB2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation NF-kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon indu
ImmunogenImmunogen: TAB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TAB2. Buffer: TAB2 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[TAB2; CHTD2; MAP3K7IP2; KIAA0733; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAB-2; TGF-beta activated kinase 1/MAP3K7 binding protein 2], [TAB2; TAB2; CHTD2; TAB-2; MAP3K7IP2; KIAA0733; MAP3K7IP2; TAB-2]
Gene, Accession #[TAB2], Gene ID: 23118, NCBI: NP_055908, UniProt: Q9NYJ8
Catalog #MBS150644
Price$375
Order / More InfoTAB2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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