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Antigenic Specificity | TAB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TAB2 antibody is human specific. TAB2 antibody is predicted not to cross-react with other TAB proteins. TAB2 Antibody: TAB2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation NF-kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1; upon indu |
Immunogen | Immunogen: TAB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TAB2. Buffer: TAB2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TAB2; CHTD2; MAP3K7IP2; KIAA0733; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAB-2; TGF-beta activated kinase 1/MAP3K7 binding protein 2], [TAB2; TAB2; CHTD2; TAB-2; MAP3K7IP2; KIAA0733; MAP3K7IP2; TAB-2] |
Gene, Accession # | [TAB2], Gene ID: 23118, NCBI: NP_055908, UniProt: Q9NYJ8 |
Catalog # | MBS150644 |
Price | $375 |
Order / More Info | TAB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |