Paxillin (Ser-83), phospho-specific Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPaxillin (Ser-83), phospho-specific
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionThis antibody was affinity purified using phospho-Paxillin (Ser-83) peptide (without carrier). The antibody detects a 68kDa* protein corresponding to the molecular mass of phosphorylated paxillin on SDS-PAGE immunoblots of NGF treated rat PC12 cells, as well as calyculin A treated human A431 cells and mouse macrophages. Paxillin, a focal adhesion protein, is involved in focal adhesion formationduring cell adhesion and migration. Paxillin contains LD motifs, LIMdomains, and SH3-/SH2-binding domains that participate in a variety of protein-protein interactions with kinases, GTPase-activating proteins, and cytoskeletal proteins. Phosphorylation of paxillin occurs at both tyrosine and serine sites. Serine phosphorylation of paxillin occurs in r
ImmunogenImmunogen: Phospho-Paxillin (Ser-83) synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 83 of mouse paxillin.This sequence is highly conserved in rat and human paxillin and is also found in all isoforms (a, b, g) of paxillin.
Other Names[Paxillin], [Pxn; Pxn; Pxn]
Gene, Accession #Gene ID: 360820, NCBI: NP_001012147.1, UniProt: Q66H76
Catalog #MBS472048
Price$385
Order / More InfoPaxillin (Ser-83), phospho-specific Antibody from MYBIOSOURCE INC.
Product Specific References• Huang, C. et al. (2004) J Cell Biol. 164(4):593-602.• Ishibe, S. et al. (2004) Mol. Cell 16 :257-267.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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