TET1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TET1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TET1 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with TET2 and TET3. TET1, a member of the ten-eleven-translocation (TET) family of genes, was initially discovered as a fusion partner of MLL in acute myeloid leukemias containing the t(10;11)(q22;q23) (1). It is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine (2). TET1 expression is regulated during inflammation in both THP-1 and primary dendritic cells, and is a negative transcriptional regulator of IL-1beta following and inflammatory stimulus (3). Recent evidence has shown that TET1 is part of a signaling pathway that regulates breast cancer growth and metastasis (4). |
| Immunogen | Immunogen: TET1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET1. Buffer: TET1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [TET1; LCX; CXXC6; bA119F7.1; KIAA1676; LCX; Methylcytosine dioxygenase TET1; CXXC-type zinc finger protein 6; tet methylcytosine dioxygenase 1], [TET1; TET1; LCX; CXXC6; bA119F7.1; CXXC6; KIAA1676; LCX] |
| Gene, Accession # | [TET1], Gene ID: 80312, NCBI: NP_085128, UniProt: Q8NFU7 |
| Catalog # | MBS153337 |
| Price | $375 |
| Order / More Info | TET1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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