MyD88 (IN) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMyD88 (IN)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunoblot
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DescriptionSpecificity: Anti-MYD88 (IN) [Rabbit antibody to peptide corresponding to aa 233-248 of human MyD88.]. This antibody recognizes human and mouse MyD88 (35 kD). Cellular responses induced by the proinflammatory cytokine IL-1 require IL-1 receptor complex (IL-1R1 and IL- 1RacP). Recently, MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor. Dominant negative mutants of MyD88 attenuate IL-1Rmediated NF- kappa B activation. MyD88 also functions as a regulator molecule for IL- 18 receptor and human Toll receptor, members of the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in loss of cellular responses to IL-1 and IL-18, and MyD88-d
ImmunogenAntigen: Peptide corresponding to aa 233-248 of human MyD88. The sequence differs from mouse MyD88 by two amino acids.
Other Names[MYD88 (IN); MyD88 (IN)], [MYD88; MYD88; MYD88D]
Gene, Accession #Gene ID: 4615, NCBI: AAC50954.1, UniProt: Q99836
Catalog #MBS194118
Price$415
Order / More InfoMyD88 (IN) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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