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Antigenic Specificity | Human Von Willebrand Factor |
Clone | [F8/44/20] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, k |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 0.1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Von Willebrand Factor (This antibody is specific for human Von Willebrand factor.). Anti-Human Von Willebrand Factor monoclonal antibody binds Von Willebrand Factor (vWF), a 270 KDa multimeric plasma glycoprotein involved in haemostasis. vWF binds to specific platelet membrane glycoproteins and exposed connective tissue to mediate the adhesion of platelets to sites of vascular damage. Blood clotting Factor VIII is maintained as a stable inactive form while binding vWF in regular blood circulation. Factor VIII is degraded rapidly when released from vWF and this release is mediated by the action of thrombin. A deficiency in vWF results in the bleeding disorder, Von Willebrand disease |
Immunogen | Immunization: Mouse monoclonal antibodies raised against Von Willebrand factor from human plasma. Presentation: Biotin and FITC conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. |
Other Names | [Von Willebrand Factor, Biotin (clone: F8/44/20) (mouse IgG1,k); Human Von Willebrand Factor], [VWF; VWF; VWD; F8VWF; F8VWF; vWF] |
Gene, Accession # | Gene ID: 7450, NCBI: NP_000543.2, UniProt: P04275 |
Catalog # | MBS520648 |
Price | $285 |
Order / More Info | Human Von Willebrand Factor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |