EWSR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEWSR1
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG2b
Formataffinity purified
Size0.1 mL
Concentration100ug/100ul
ApplicationsImmunofluorescence (IF), Western Blot (WB)
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Descriptionn/a
ImmunogenImmunogen: Ewing sarcoma breakpoint region 1 is a protein belonging to the family of RNA binding proteins which contain a single RRM domain. It also has a single Zinc Finger domain of the ZnF_RBZ subtype found in Ran binding proteins. Ran is a small G protein related to p21-Ras which regulates the import and export of proteins to the nucleus. EWSR1 appears to be a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing
Other Names[EWSR1], [EWSR1; EWSR1; EWS; bK984G1.4; EWS]
Gene, Accession #[EWSR1], Gene ID: 2130, NCBI: CAG30376.1, UniProt: Q96FE8
Catalog #MBS415255
Price$370
Order / More InfoEWSR1 Antibody from MYBIOSOURCE INC.
Product Specific References1: Azuma M, Embree LJ, Sabaawy H, Hickstein DD. Ewing sarcoma protein ewsr1 maintains mitotic integrity and proneural cell survival in the zebrafish embryo. PLoS One. 2:e979 (2007).2: Delattre O, Zucman J, Plougastel B, Desmaze C, Melot T, Peter M, Kovar H, Joubert I, de Jong P, Rouleau G, et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature. 359:162-5 (1992).3. Andersson MK, StAYhlberg A, Arvidsson Y, Olofsson A, Semb H, Stenman G, Nilsson O, Aman P. The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response. BMC Cell Biol. 11:9:37 (2008).4: Felsch JS, Lane WS, Peralta EG. Tyrosine kinase Pyk2 mediates G-protein-coupled receptor regulation of the Ewing sarcoma RNA-binding protein EWS. Curr Biol. 9:485-8 (1999).5: Belyanskaya LL, Delattre O, Gehring H.Expression and subcellular localization of Ewing sarcoma (EWS) protein is affected by the methylation process. Exp Cell Res. Aug 15;288(2):374-81 (2003). Exp Cell Res. 288:374-81 (2003).6: Leemann-Zakaryan RP, Pahlich S, Sedda MJ, Quero L, Grossenbacher D, Gehring H. Dynamic subcellular localization of the Ewing sarcoma proto-oncoprotein and its association with and stabilization of microtubules. J Mol Biol. 386:1-13 (2009).7. Da Cruz S, Cleveland DW. Understanding the role of TDP-43 and FUS/TLS in ALS and beyond. Curr Opin Neurobiol. [Epub ahead of print] (2011).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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