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Antigenic Specificity | Synaptotagmin-6 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot (IB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human, mouse and rat Synaptotagmin-6. It does not cross-react with other Synaptotagmins. Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N terminal transmembrane region (TMR), a variable linker,and two C-terminal C2 domains: C2A and C2B. There are 15 members in the mammalian synaptotagmin family. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to act as Ca+2 sensors in vesicular trafficking and exocytosis. Calcium binding to synaptotagmin triggers neurotransmitter release at the synapse. The first C2 domain mediates -dependent phospholipid binding. Ca+2 The second C2 domain mediates interaction with Stonin 2. Synaptotagmin-6 is localized |
Immunogen | Antigen: Fusion protein corresponding to aa 246-333 of mouse Synaptotagmin-6 (accession no.Q9R0N8). |
Other Names | [Synaptotagmin-6], [SYT6; SYT6; sytVI; SytVI] |
Gene, Accession # | Gene ID: 148281, NCBI: NP_001257734.1 |
Catalog # | MBS190916 |
Price | $410 |
Order / More Info | Synaptotagmin-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |