MAGEL2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAGEL2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.6 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total MAGEL2 protein. Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the N terminal of human MAGE-like 2
Other Names[PWLS; nM15; NDNL1]
Gene, Accession #[MAGEL2], NCBI: Q9UJ55.2, UniProt: Q9UJ55
Catalog #MBS9412156
Price$255
Order / More InfoMAGEL2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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