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Antigenic Specificity | UBA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Immunogen | Immunogen: Recombinant protein of human UBA3 (NP 003959.3). |
Other Names | [NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1 catalytic subunit; ubiquitin like modifier activating enzyme 3; NEDD8-activating enzyme E1C; Ubiquitin-activating enzyme E1C; Ubiquitin-like modifier-activating enzyme 3; Ubiquitin-activating enzyme 3] |
Gene, Accession # | [UBA3], Gene ID: 9039, NCBI: Q8TBC4.2, UniProt: Q8TBC4 |
Catalog # | MBS8569804 |
Price | $280 |
Order / More Info | UBA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |