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Antigenic Specificity | CD45 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous CD45 proteins. Protein tyrosine phosphatase, receptor type C encoded by PTPRC is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Mouse CD45; PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD45] |
Gene, Accession # | [CD45], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575 |
Catalog # | MBS9700270 |
Price | $250, $250 |
Order / More Info | CD45 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |