Human EpCAM/TROP-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human EpCAM/TROP-1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 100ug/100ul |
| Applications | Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody reacts with Trop-1 present on trophoblast cells and on human choriocarcinomas. The antigen has also been detected on 4 of 4 human choriocarcinoma cell lines tested, on a fibrosarcoma cell line (HT1080C), on an erythroleukemia cell line (K562) and on the majority of human malignant epithelial cells and fetal epithelial precursors. A carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital |
| Immunogen | Immunogen: Human choriocarcinoma cell line BeWo |
| Other Names | n/a |
| Gene, Accession # | [TROP-1] |
| Catalog # | MBS418469 |
| Price | $370 |
| Order / More Info | Human EpCAM/TROP-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lipinski M, et al. Human trophoblast cell-surface antigens defined by monoclonal antibodies. Proc. Natl. Acad. Sci. USA 78: 5147-5150, 1981. Strnad J, et al. Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA. Cancer Res. 49: 314-317, 1989. Klein CE, et al. Expression of 38-kD cell-surface glycoprotein in transformed human keratinocyte cell lines, basal cell carcinomas, and epithelial germs. J. Invest. Dermatol. 95: 74-82, 1990. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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