RhoA (Ser-188), phospho-specific Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | RhoA (Ser-188), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was affinity purified using phospho-Rho (Ser-188) peptide (without carrier). The antibody detects a RhoA GST fusion protein when phosphorylated with PKA, but does not detect the unphosphorylated recombinant protein. Rho (A, B, & C) proteins are members of the Ras superfamily of GTPases. These proteins regulate a variety of cellular functions, including cell cycle progression, cytoskeletal rearrangement, and gene expression. Rho cycles between the active GTP-bound form and an inactive GDPbound form. Interconversion between these forms is controlled by guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). The Rho proteins RhoA, RhoB, and RhoC are highly homologous and contain the consensus amino acid |
| Immunogen | Immunogen: Phospho-RhoA (Ser-188) synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 188 of human RhoA. This peptide sequence is highly conserved in rat and mouse RhoA, but is not found in RhoB or RhoC proteins. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS472056 |
| Price | $385 |
| Order / More Info | RhoA (Ser-188), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Lang, P. et al. (1996) EMBO J. 15:510.• Dong, J.M. et al. (1998) J. Biol. Chem. 273(35):22554.• Sawada, N. et al. (2001) Biochem. Biophys. Res. Commun. 280:798.• Ellerbroek, S.M. et al. (2003) J. Biol. Chem. 278(21):19023. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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