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Antigenic Specificity | MUL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MUL1 protein. MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1) is a Protein Coding gene. Among its related pathways are Deubiquitination and Metabolism of proteins. Exhibits weak E3 ubiquitin-protein ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Can ubiquitinate AKT1 preferentially at Lys-284 involving Lys-48-linked polyubiquitination and seems to be involved in regulation of Akt signaling by targeting phosphorylated Akt to proteosomal degradation. Proposed to preferentially act as a SUMO E3 ligase at physiological concentrations. Plays a role in the control |
Immunogen | Immunogen: Synthesized peptide derived from part region of human MUL1 protein |
Other Names | [Rabbit MUL1; Mitochondrial ubiquitin ligase activator of NFKB 1; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; Growth inhibition and death E3 ligase; Mitochondrial-anchored protein ligase; MAPL; Putative NF-kappa-B-activating protein 266; RING finger protein 218; RING-type E3 ubiquitin transferase NFKB 1] |
Gene, Accession # | [MUL1], Gene ID: 79594, NCBI: NP_078820, UniProt: Q969V5 |
Catalog # | MBS9709900 |
Price | $130, $220, $325 |
Order / More Info | MUL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |