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Antigenic Specificity | ADORA2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ADORA2B antibody is human, mouse and rat reactive. At least two isoforms of ADORA2B are known to exist; this antibody will detect both isoforms. ADORA2B antibody is predicted to not cross-react with ADORA2A. The adenosine receptor ADORA2B is a member of the G protein-coupled receptor superfamily and is an integral membrane protein that stimulates adenylate cyclase activity in the presence of adenosine (1,2). Extracellular adenosine triggers a potent anti-inflammatory response that is mediated in part by ADORA2B including the stimulation of IL-10 production (3-5). Activation of ADORA2B can also enhance the abundance of regulatory T cells (Tregs), a class of cells that work to constrain inflammation (6). |
Immunogen | Immunogen: ADORA2B antibody was raised against a 19 amino acid peptide near the amino terminus of human ADORA2B. Buffer: ADORA2B antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Adenosine receptor A2b; ADORA2; adenosine A2b receptor], [ADORA2B; ADORA2B; ADORA2] |
Gene, Accession # | [ADORA2B], Gene ID: 136, NCBI: NP_000667, UniProt: P29275 |
Catalog # | MBS153447 |
Price | $375 |
Order / More Info | ADORA2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |