Human Complement Factor B/Bb Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Complement Factor B/Bb |
| Clone | [M13/12] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 k |
| Format | fluorescein (FITC) conjugate |
| Size | 0.1 mg |
| Concentration | 0.1 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Complement Factor B/Bb. Anti-human complement factor B/Bb recognizes human complement factor B and its' cleavage product Bb. Complement factor B is a single-chain molecule of 764 amino acids (MW of 90 kDa) and is part of the alternative complement pathway. It is cleaved by Factor D yielding the non-catalytic Ba and the serine protease Bb. Bb associates with C3b and provides the catalytic subunit of the C5 convertase which cleaves C5 to C5a and C5b. Factor B is an acute-phase protein whose levels increase during inflammation. Additionally, Bb is involved in the proliferation and differentiation of pre-activated B-lymphocytes. Conversely, Ba has been shown to inhibit the proliferation of pre-activated B-lymphocytes. |
| Immunogen | Hybridoma Production: Immunization: Immunization: Mouse monoclonal antibody raised against human complement factor B/Bb. Isotype Control: CLCMG101 |
| Other Names | [Human Complement Factor B/Bb], [CFB; CFB; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; BF; BFD; GBG] |
| Gene, Accession # | Gene ID: 629, NCBI: NP_001701.2 |
| Catalog # | MBS520699 |
| Price | $305 |
| Order / More Info | Human Complement Factor B/Bb Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Oppermann, M., Baumgarten, H., Brandt, E., Gottsleben, W., Kurts, C., and Gotze, O. (1990) J. Immunol. Methods 133, 181-1902.2. Oppermann, M., Kurts, C., Zierz, R., Quentin, E., Weber, M. H., and Gotze, O. (1991) Kidney Int. 40, 939- 947.3. Oppermann, M., Hopken, U., and Gotze, O. (1992) Immunopharm. 24, 119-134. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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