AIFM3 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-AIFM3 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | AIFM3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3). AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and ultimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation. Multiple isoforms of AIFM3 are known to exist. |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 16 amino acid peptide from near the center of human AIFM3. |
| Other Names | [Apoptosis-inducing factor mitochondrion-associated 3, AIFL] |
| Gene, Accession # | [AIFM3], Gene ID: 150209, NCBI: NP_001018070.1, UniProt: Q96NN9 |
| Catalog # | MBS9403508 |
| Price | $320 |
| Order / More Info | AIFM3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies