FGD4 (N-term), 157-186 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FGD4 (N-term), 157-186 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.45 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This FGD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the N-terminal region of human FGD4. This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intra |
| Immunogen | n/a |
| Other Names | [FYVE; RhoGEF and PH domain-containing protein 4; Actin filament-binding protein frabin; FGD1-related F-actin-binding protein; Zinc finger FYVE domain-containing protein 6; FGD4; FRABP; ZFYVE6] |
| Gene, Accession # | [FGD4], Gene ID: 121512, NCBI: NP_640334.2, UniProt: Q96M96 |
| Catalog # | MBS9204764 |
| Price | $165, $370 |
| Order / More Info | FGD4 (N-term), 157-186 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Rose, J. Phd, et al. Mol. Med. (2010) In press : Fabrizi, G.M., et al. Neurology 72(13):1160-1164(2009) Houlden, H., et al. Neurology 72(7):617-620(2009) Horlock, C., et al. Int. Arch. Allergy Immunol. 150(3):237-251(2009) Stendel, C., et al. Am. J. Hum. Genet. 81(1):158-164(2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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