BCL-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBCL-3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: BCL-3 antibody detects endogenous levels of BCL-3. Function: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity).Subunit Structure: Component of a complex consisting of the NF-kappa-B p52-p52 homodimer and BCL3. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Interacts with N4BP2, COPS5 and PIR. Interacts with CYLD (By similarity).Post-translational Modifications: Polyubiquitinated. Ubiquitination vi
ImmunogenImmunogen: A synthesized peptide derived from human BCL-3 Subcellular Location: Nucleus. Cytoplasm. Cytoplasm > Perinuclear Region. Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
Other Names[B cell CLL/lymphoma 3; B cell leukemia/lymphoma 3; B cell lymphoma 3 encoded protein; B-cell lymphoma 3 protein; Bcl 3; BCL 4; BCL-3; Bcl3; BCL3_HUMAN; BCL4; Chronic lymphatic leukemia protein; D19S37; Protein Bcl 3; Proto-oncogene BCL3]
Gene, Accession #[BCL-3], Gene ID: 602, NCBI: NP_005169.2, UniProt: P20749
Catalog #MBS9603175
Price$240, $280
Order / More InfoBCL-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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