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Antigenic Specificity | Phospho-PAK1/2/3-T423/402/421 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding T423/402/421 of human PAK1/2/3 |
Other Names | [Phospho-PAK1/PAK2/PAK3-T423/T402/T421: p21-activated kinase 1; PAK-1; p65-PAK; Alpha-PAK], [PAK1; PAK1; PAKalpha; PAK-1] |
Gene, Accession # | [PAK1/PAK2/PAK3], Gene ID: 5058, NCBI: Q13153.2, UniProt: Q13153 |
Catalog # | MBS128378 |
Price | $235, $350, $525 |
Order / More Info | Phospho-PAK1/2/3-T423/402/421 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |