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Antigenic Specificity | Human CD54 |
Clone | [15.2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen. |
Immunogen | n/a |
Other Names | [Human CD54; Intercellular adhesion molecule 1; Icam1; MALA-2; MyD10; CD54; Icam-1] |
Gene, Accession # | [CD54], Gene ID: 3383, NCBI: NP_000192.2, UniProt: P05362 |
Catalog # | MBS2553819 |
Price | $75, $135 |
Order / More Info | Human CD54 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Voraberger G, et al. 1991. J. Immunol. 147:2777. 2. Staunton DE, et al. 1988. Cell 52:925. 3. Greve JM, et al. 1989. Cell 56:839. |