ISG15 (N-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityISG15 (N-term)
Clone[1031CT2.8.3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1,k
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis ISG15 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-165 amino acids from the N-terminal region of human ISG15. Ubiquitin-like protein which plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein. ISGylation involves a cascade of enzymatic reactions involving E1, E2, and E3 enzymes which catalyze the conjugation of ISG15 to a lysine residue in the target protein. Its target proteins include IFIT1, MX1/MxA, PPM1B, UBE2L6, UBA7, CHMP5, CHMP2A, CHMP4B and CHMP6. Can also isgylate: EIF2AK2/PKR which results in its activation, DDX58/RIG-I which inhibits its function in ant
Immunogenn/a
Other Names[Ubiquitin-like protein ISG15; Interferon-induced 15 kDa protein; Interferon-induced 17 kDa protein; IP17; Ubiquitin cross-reactive protein; hUCRP; ISG15; G1P2; UCRP]
Gene, Accession #[ISG15], Gene ID: 9636, NCBI: NP_005092.1, UniProt: P05161
Catalog #MBS9217047
Price$165, $370
Order / More InfoISG15 (N-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBlomstrom D.C.,et al.J. Biol. Chem. 261:8811-8816 (1986). Reich N.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6394-6398 (1987). Knight E. Jr.,et al.J. Biol. Chem. 263:4520-4522 (1988). Knight E. Jr.,et al.J. Biol. Chem. 263:10040-10040 (1988). Kamitani T.,et al.Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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