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Antigenic Specificity | SOX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOX2 Antibody: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. SOX2 is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. The role of SOX2 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created b |
Immunogen | Immunogen: SOX2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SOX. Buffer: SOX2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SOX2; ANOP3; MCOPS3; Transcription factor SOX-2; SRY (sex determining region Y)-box 2], [SOX2; SOX2; ANOP3; MCOPS3] |
Gene, Accession # | [SOX2], Gene ID: 6657, NCBI: NP_003097, UniProt: P48431 |
Catalog # | MBS150482 |
Price | $375 |
Order / More Info | SOX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |