Edit |   |
---|---|
Antigenic Specificity | c-Fos |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | c-Fos is part of the Fos gene family; which consists of 4 members: FOS, FOSb, FOSL1 and FOSL2. Fos family genes are associated with JUN proteins and other basic leucine ipper (bZIP) domain proteins to create a variety of AP-1 (activator protein-1) complexes. c-Fos is considered to be an immediate-early gene because expression is normally low but rapidly and transiently in response to a wide array of stimuli including serum, growth factors, tumor promoters, cytokines, and UV radiation. It plays an important role in many cellular functions, and is over-expressed in variety of cancers. Left: c-Fos staining (green) in HeLa cells, which were treated with serum-starvation for 36 hours, followed by 2 hours, 20% FBS stimulation (bottom panel), or P |
Immunogen | n/a |
Other Names | [c-fos; Proto-oncogene c-Fos; proto-oncogene c-Fos; Fos proto-oncogene, AP-1 transcription factor subunit; Cellular oncogene fos; G0/G1 switch regulatory protein 7], [FOS; FOS; p55; AP-1; C-FOS; G0S7] |
Gene, Accession # | [c-Fos], Gene ID: 2353, NCBI: CAA24756.1, UniProt: P01100 |
Catalog # | MBS555684 |
Price | $405 |
Order / More Info | c-Fos Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |