BCAS3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBCAS3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionBCAS3 Antibody: The Breast carcinoma amplified sequence (BCAS3) gene is localized to 17q23, a region that is often amplified in breast cancers. Copy number gains at this region have also been reported in other tumors such as brain, lung, liver, testis and bladder. BCAS3 is thought to be an estrogen receptor (ER)-alpha co-activator that acts through PELP1, another ER-alpha that in turn activates BCAS3 expression. This may set up a positive feedback loop leading to ER-a signal amplification in the cell which may play a significant role in breast cancer. BCAS3 expression has also been observed in embryonic stem cells and vascular precursors, suggesting that it may also play a role in embryogenesis and tumor angiogenesis.
ImmunogenImmunogen: BCAS3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human BCAS3. Buffer: BCAS3 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[BCAS3; MAAB; GAOB1; Breast carcinoma-amplified sequence 3; breast carcinoma amplified sequence 3], [BCAS3; BCAS3; MAAB; GAOB1]
Gene, Accession #[BCAS3], Gene ID: 54828, NCBI: EAW51415, UniProt: Q9H6U6
Catalog #MBS150707
Price$375
Order / More InfoBCAS3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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