Edit |   |
---|---|
Antigenic Specificity | SLAMF1 (Y307), 289-317 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.45 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SLAMF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from human SLAMF1. SLAMF1 is high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
Immunogen | n/a |
Other Names | [Signaling lymphocytic activation molecule; CDw150; IPO-3; CD150; SLAMF1; SLAM] |
Gene, Accession # | [SLAMF1], Gene ID: 6504, NCBI: NP_003028.1, UniProt: Q13291 |
Catalog # | MBS9209500 |
Price | $165, $370 |
Order / More Info | SLAMF1 (Y307), 289-317 Antibody from MYBIOSOURCE INC. |
Product Specific References | Mikhalap S.V., Shlapatska L.M., Berdova A.G., Law C.L.,J. Immunol. 162:5719-5727(1999) Tatsuo H., Ono N., Tanaka K., Yanagi Y.Nature 406:893-897(2000) Sayos J., Wu C., Morra M., Wang N., Zhang X., Allen D., van Schaik S.,Nature 395:462-469(1998) |