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Antigenic Specificity | PIH1D1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PIH1D1 Antibody detects endogenous levels of PIH1D1. Description: Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).Subunit Structure: Component of the R2TP complex composed at least of PIHD1, RUVBL1, RUVBL2 and RPAP3 (PubMed:20864032). Interacts with phosphorylated TELO2 and mediates interaction of TELO2 with the R2TP co |
Immunogen | Immunogen: A synthesized peptide derived from human PIH1D1. Tissue Specificity: Expressed at low levels in normal mammary epithelial cells (at protein level) (PubMed:24036451). Highest expression in lung, leukocyte and placenta. Expressed at lower levels in brain, prostate, colon, heart, small intestine, liver, ovary, pancreas, skeletal muscle, spleen, testis and thymus (PubMed:21078300). |
Other Names | [PIH1 domain-containing protein 1; PIH1 domain-containing protein 1; PIH1 domain-containing protein 1; PIH1 domain containing 1; Nucleolar protein 17 homolog] |
Gene, Accession # | [PIH1D1], Gene ID: 55011, NCBI: NP_060386.1, UniProt: Q9NWS0 |
Catalog # | MBS9611448 |
Price | $240, $280 |
Order / More Info | PIH1D1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |