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Antigenic Specificity | BAX - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, human, porcine |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against BAX. It was validated on Western Blot and immunohistochemistryTarget Description: BAX encodes a protein that belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. BAX expression is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BAX |
Other Names | [apoptosis regulator BAX isoform alpha; Apoptosis regulator BAX; apoptosis regulator BAX; BCL2 associated X, apoptosis regulator; Bcl-2-like protein 4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: NP_620116, UniProt: Q07812 |
Catalog # | MBS3224344 |
Price | $270 |
Order / More Info | BAX - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |