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Antigenic Specificity | PI3 Kinase p85/p55(phospho-Tyr467/199) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total PI3 Kinase p85/p55 only when phosphorylated at tyrosine 467/199. Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3 Kinase p85/p55. |
Other Names | [p85, AGM7, p85-ALPHA, p55, p55-GAMMA] |
Gene, Accession # | Gene ID: 5295, NCBI: NP_001229395.1, UniProt: P27986 |
Catalog # | MBS9404477 |
Price | $200, $255 |
Order / More Info | PI3 Kinase p85/p55(phospho-Tyr467/199) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |