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Antigenic Specificity | Plexin D1 (Sema Domain) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was affinity purified using Plexin D1 (Sema Domain) peptide (without carrier). The antibody detects 250, 215, and 195 kDa bands corresponding to the apparent molecular mass of Plexin D1 variants in human umbilical vein endothelial cells. Plexins are a family of large integral membrane proteins that complex with neuropilins to form semaphorin co-receptors. The extracellular region of plexins contains a semaphorin domain, multiple glycine-rich motifs, and MET-related sequences. The cytoplasmic region contains a Sex/Plexin domain and putative tyrosine phosphorylation sites that mediate signal transduction after activation. Plexin D1 is a type I transmembrane protein that may be expressed as multiple isoforms in many cell types, i |
Immunogen | Immunogen: Plexin D1 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the semaphorin domain from human Plexin D1. This sequence is well conserved in rat and mouse Plexin D1, and has low homology to other Plexin family members. |
Other Names | [PLXND1; Sema3E], [PLXND1; PLXND1; PLEXD1; KIAA0620] |
Gene, Accession # | Gene ID: 23129, NCBI: AAH62465.1, UniProt: Q9Y4D7 |
Catalog # | MBS474129 |
Price | $385 |
Order / More Info | Plexin D1 (Sema Domain) Antibody from MYBIOSOURCE INC. |
Product Specific References | van der Zwaag, B. et al. (2002) Dev Dyn. 2002 Nov;225(3):336-43.Deutsch, U. (2004) Dev Cell. 7(1):1.Casazza, A. et al. (2010) J Clin Invest. 120(8):2684. |