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Antigenic Specificity | MEKK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 3(MAP3K3) detection. Tested with WB, IHC-P in Mouse, Rat. Background: MAP3K3(Mitogen-activated protein kinase kinase kinase 3), also known as MAP/ERK KINASE KINASE 3, MEKK3 or MAPKKK3, is an enzyme that in humans is encoded by the MAP3K3 gene. MAP3K3 is contiguously distal to LYK5 on chromosome 17(Puffenberger et al., 2007). By yeast 2-hybrid analysis of a mouse T-cell cDNA library, Uhlik et al.(2003) showed that a C-terminal fragment of mouse Osm(CCM2) interacted with Mekk3, which activates p38 in response to sorbitol-induced hyperosmotic conditions. Mekk3 and Osm colocalized in the cytoplasmic compartment of cotransfected cells, and the Mekk3-Os |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse MEKK3 (11-25aa MKDLVALQMSRRTRL), different from the related rat sequence by two amino acids. |
Other Names | [Mitogen-activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; M3K3_HUMAN; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; MEKK3; mitogen activated protein kinase kinase kinase 3; Mitogen-activated protein kinase kinase kinase 3], [Map3k3; Map3k3; Mekk3; MAPKKK3; AW548911; mKIAA4031; Mekk3; MEK kinase 3; MEKK 3] |
Gene, Accession # | [MAP3K3], Gene ID: 26406, NCBI: Q61084.1, UniProt: Q61084 |
Catalog # | MBS176013 |
Price | $315 |
Order / More Info | MEKK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |