MEKK3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMEKK3
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase kinase kinase 3(MAP3K3) detection. Tested with WB, IHC-P in Mouse, Rat. Background: MAP3K3(Mitogen-activated protein kinase kinase kinase 3), also known as MAP/ERK KINASE KINASE 3, MEKK3 or MAPKKK3, is an enzyme that in humans is encoded by the MAP3K3 gene. MAP3K3 is contiguously distal to LYK5 on chromosome 17(Puffenberger et al., 2007). By yeast 2-hybrid analysis of a mouse T-cell cDNA library, Uhlik et al.(2003) showed that a C-terminal fragment of mouse Osm(CCM2) interacted with Mekk3, which activates p38 in response to sorbitol-induced hyperosmotic conditions. Mekk3 and Osm colocalized in the cytoplasmic compartment of cotransfected cells, and the Mekk3-Os
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse MEKK3 (11-25aa MKDLVALQMSRRTRL), different from the related rat sequence by two amino acids.
Other Names[Mitogen-activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; M3K3_HUMAN; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; MEKK3; mitogen activated protein kinase kinase kinase 3; Mitogen-activated protein kinase kinase kinase 3], [Map3k3; Map3k3; Mekk3; MAPKKK3; AW548911; mKIAA4031; Mekk3; MEK kinase 3; MEKK 3]
Gene, Accession #[MAP3K3], Gene ID: 26406, NCBI: Q61084.1, UniProt: Q61084
Catalog #MBS176013
Price$315
Order / More InfoMEKK3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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