AGER (Center) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-AGER (Center) antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | AGER (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This AGER antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 174-208 amino acids from the Central region of human AGER. Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF- alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, an |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products; AGER; RAGE] |
| Gene, Accession # | [AGER], Gene ID: 177, NCBI: NP_001127.1, UniProt: Q15109 |
| Catalog # | MBS9216606 |
| Price | $150 |
| Order / More Info | AGER (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Neeper M.,et al.J. Biol. Chem. 267:14998-15004(1992).Sugaya K.,et al.Genomics 23:408-419(1994).Abedin M.J.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.Malherbe P.,et al.Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.Yonekura H.,et al.Biochem. J. 370:1097-1109(2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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