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Antigenic Specificity | CHRNA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Recombinant protein of human CHRNA4 |
Other Names | [EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4] |
Gene, Accession # | [CHRNA4], Gene ID: 1137, NCBI: NP_000735.1, UniProt: P43681 |
Catalog # | MBS9130252 |
Price | $200, $275, $430 |
Order / More Info | CHRNA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |