beta-Tubulin Antibody from MYBIOSOURCE INC.

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Antigenic Specificitybeta-Tubulin
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
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DescriptionTubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are alpha-tubulin and beta-tubulin, the proteins that make up microtubules. Each has a molecular weight of approximately 55 kiloDaltons. Microtubules are assembled from dimers of alpha- and beta-tubulin. These subunits are slightly acidic with an isoelectric point between 5.2 and 5.8.1 Mutant huntingtin, disrupted intracellular transport and insulin secretion by direct interference with microtubular beta-tubulin. Mutant huntingtin impaired glucose-stimulated insulin secretion in insulin-producing beta cells, without altering stored levels of insulin. Smith et al. (2009) proposed a novel pathogenetic process by which mutant
ImmunogenImmunogen: Human beta-Tubulin protein with full length.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS355046
Price$250
Order / More Infobeta-Tubulin Antibody from MYBIOSOURCE INC.
Product Specific References1. Williams RC Jr, Shah C, Sackett D (November 1999). Separation of tubulin isoforms by isoelectric focusing in immobilized pH gradient gels. Anal Biochem 275 (2): 265-7. 2. Smith, R., Bacos, K., Fedele, V., Soulet, D., Walz, H. A., Obermuller, S., Lindqvist, A., Bjorkqvist, M., Klein, P., Onnerfjord, P., Brundin, P., Mulder, H., Li, J.-Y. Mutant huntingtin interacts with beta-tubulin and disrupts vesicular transport and insulin secretion. Hum. Molec. Genet. 18: 3942-3954, 2009.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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