CENPC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCENPC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: CENPC1 antibody detects endogenous levels of total CENPC1. Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.Subunit Structure: Oligomer. Component of the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and CENPU (PubMed:16622419). The CENPA-NAC complex in
ImmunogenImmunogen: A synthesized peptide derived from human CENPC1 Subcellular Location: Nucleus. Chromosome > Centromere > Kinetochore. Localizes exclusively in the kinetochore domain of centromeres. Tissue Specificity: Expression varies across the cell cycle, with high levels in G2 phase (at the mRNA level). Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Horse (83%), Sheep (100%), Rabbit (92%), Dog (100%)
Other Names[CENP-C 1; CENP-C; CENPC_HUMAN; CENPC1; Centromere autoantigen C; Centromere autoantigen C1; Centromere protein C 1; Centromere protein C; hcp-4; ICEN7; Interphase centromere complex protein 7; MIF2]
Gene, Accession #[CENPC1], Gene ID: 1060, NCBI: NP_001803.2, UniProt: Q03188
Catalog #MBS9609374
Price$240, $280
Order / More InfoCENPC1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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