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Antigenic Specificity | Phospho-IRF-3 (Ser15) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: bovine, horse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-IRF-3 (Ser15) Antibody detects endogenous levels of IRF-3 only when phosphorylated at Ser15. Description: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral i |
Immunogen | Immunogen: A synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser15. Tissue Specificity: Expressed constitutively in a variety of tissues. |
Other Names | [IIAE7; Interferon regulatory factor 3; IRF 3; IRF-3; IRF3; IRF3_HUMAN; MGC94729] |
Gene, Accession # | [IRF-3], Gene ID: 3661, NCBI: NP_001184053.1, UniProt: Q14653 |
Catalog # | MBS9610749 |
Price | $225, $280, $340 |
Order / More Info | Phospho-IRF-3 (Ser15) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |