Human CEACAM5,6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CEACAM5,6 |
| Clone | [MUS] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry, CELISA, ELISA (EIA), Western Blot (WB) and Immunohistology on cryosections |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human CEACAM5,6 (CEA;NCA,CD66c). Background: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family (1). The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker (2). CEACAM6 expression is strongly upregulated already during early stages of adenoca |
| Immunogen | Immunogen: Immunogen: extracted protein of CEACAM5 |
| Other Names | [CEA; NCA; CD66ce], [CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA] |
| Gene, Accession # | Gene ID: 1048, NCBI: NP_001278413.1, UniProt: P06731 |
| Catalog # | MBS468031 |
| Price | $505 |
| Order / More Info | Human CEACAM5,6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine(T. Creighton, ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggestedfunctions and expression in normal and malignant tissues. Semin Cancer Biol. 9, 67-81.Scholzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B, Thompson J(2000). Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentiallyexpressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps andearly adenomas. Am J Pathol 156, 595-605.Grunert F, AbuHarfeil N, Schwarz K and von Kleist S (1985). Two CEA and three NCAspecies, although distinguishable by monoclonal antibodies, have nearly identical peptidepatterns. Int J Cancer 36, 357-362. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
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