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Antigenic Specificity | 3BP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of 3BP2 protein. The protein encoded by SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in SH3BP2 result in cherubism. Multiple transcript variants encoding different isoforms have been found for SH3BP2. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human 3BP2 protein at amino acid sequence of 210-290 |
Other Names | [Rabbit 3BP2; SH3 domain-binding protein 2; 3BP-2] |
Gene, Accession # | [3BP2], Gene ID: 6452, NCBI: NP_003014, UniProt: P78314 |
Catalog # | MBS9708230 |
Price | $130, $220, $325 |
Order / More Info | 3BP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |